If you have an AMD graphics card and want to run The Witcher 3: Wild Hunt with HairWorks enabled, here's a nice tweak originating from our own forums. 

It seems that the performance trade-off with HairWorks enabled takes a huge toll specifically on AMD cards. However by decreasing tessellation you can get to very normal numbers.

All you need to do is this:

• Create a profile for witcher3.exe in your Catalyst Control Center
• Set Tessellation Mode to “Override application settings”
• Set the Maximum Tessellation Level to either 2x, 4x, 8x or 16x.

We would recommend against using 2x as it severely reduces quality and looks terrible. Here’s a comparison photo that lets you see the differences between 2x, 4x, 8x and 16x tessellation levels.  AMD users have a way of enjoying The Witcher 3: Wild Hunt with the Nvidia HairWorks feature enabled and actually getting better performance than GeForce users not using a Maxwell architecture Nvidia GPU. It seems a bit ironic but exciting nonetheless.