Bethesda has released the first beta patch for Fallout 4, after the break an overview of changes. The patch offers a number of general memory and stability improvements, fixes several issues and crashes. 

There are also two new features available to try out that allow a keyboard’s number pad to be used for remapping and Remapping Activate now working on Quick Container.

Fallout 4 - First Beta Patch Changelog:

New Features
Number pad keys can now be used for remapping
Remapping Activate now works on Quick Container

Fixes
General memory and stability improvements
Fixed issue where equipped weapons become locked after completing Reunions
Fixed issue with When Freedom Calls where the quest would not complete
During Confidence Man, fixed issue where player's health would continuously regenerate
Fixed crash related to jumping into water and reloading saved games
Fixed issue where Launcher would not save God Rays Quality setting properly

In order to gain access to the game's beta patches, you’ll have to follow this guide.

Log into Steam
Right Click on Fallout 4 in your Library
Select Settings
Select Betas
A drop down menu will appear. Select Beta Update
Select OK.
Wait a few minutes and Fallout 4 should update.
When done, Fallout 4 should appear as Fallout 4 [beta] in your Library